The Episteme Project focuses on developing tools for increasing accessibility to and awareness of Ancient Scientific and Mathematical works. Unique to Episteme is its focus on representing and computing with diagrammatic information. Rather than treating diagrams as images, Episteme treats diagrams as a unique data type capable of representing a dynamic process in static form. Using this approach, both person and computer can interact with diagrams in terms of what they represent rather than how they are drawn. More specifically, Episteme explores the traditional operations of navigation, production, and logical assertion on diagrams through the lens of computation. In addition, non-traditional modes of interacting with diagrams such as querying become feasible.